Ketogenic diet could protect seniors against Alzheimer's and Parkinson's

New research conducted by specialists at the University of Coimbra in Portugal suggests that the ketogenic diet could offer significant protection against devastating brain diseases such as Alzheimer's, Parkinson's, and Huntington's disease.

The research team examined numerous previous studies that investigated the connection between the keto diet and neurodegenerative conditions. Their findings indicate that metabolic problems related to glucose processing — the body's primary energy source — play a crucial role in the development of these brain diseases, which affect older people in particular.

The brain protection mechanism

The ketogenic diet works by drastically reducing carbohydrates and increasing the intake of fats and proteins, causing the body to enter a special metabolic state known as ketosis. In this state, the body produces ketones that can serve as an alternative fuel source for the brain.

This metabolic shift appears to be especially beneficial for neurones that struggle to utilise glucose, a problem commonly seen in Alzheimer's disease. Ketones can compensate for metabolic deficits and help stabilise neuronal function in affected older adults.

Important limitations and precautions

Although the results from preliminary studies are encouraging, researchers warn that extensive further investigation is needed to confirm long-term efficacy and safety. They emphasise that many aspects of its practical application in a clinical setting remain unknown.

The ketogenic diet also presents significant challenges in implementation. It is considered one of the most difficult diets to maintain over the long term, which could affect patient adherence. In addition, it can produce unpleasant side effects such as constipation, insomnia, and raised cholesterol levels.

Previous studies have also highlighted potential long-term risks, including the possibility of developing type 2 diabetes and cardiovascular disease. For older adults considering this approach, consulting a doctor is essential in order to weigh up the benefits against individual risks and to ensure careful monitoring of their health.